21 ml
0.7 FL. OZ.


Hydroquinone, Azelaic Acid, Hydrocortisone, Aloe Vera Extract, Vitamin E
Clear stubborn dark spots and melasma with Melanex 501, a dermatologist-developed, prescription-strength dark spots treatment. Powered by Hydroquinone, this formula targets the root cause of dark spots - excess melanin production - to deliver clinically measurable improvements in clarity, tone, and brightness in as little as 5 weeks.
Find treatment
Get started




* Based on consumer testing of 483 users after 3 months of use
Hydroquinone

Potent skin-brightening agent, clinically-proven to fade dark spots and discoloration by inhibiting melanin production.
Azelaic Acid

Targets inflammation, fades dark spots, and reduces redness.
Hydrocortisone

Used short-term to ease skin sensitivity—phased out after 2 months once skin is adjusted.
Aloe Vera Extract

Calms inflammation. Reduces redness. Accelerates repair.
Vitamin E

Protects skin from free radical damage and environmental stress.








![]() | ![]() |
|---|---|
Melanex 501 | Other treatments |
Technology Patented medical-grade technology to target discoloration | Technology Standard cosmetic formulations |
Efficacy Powered by powerful Rx-strength active ingredients | Efficacy Formulated with weak over-the-counter actives. |
Results Visible improvement in 8-12 weeks | Results Visible improvement in 20-24 weeks |
Sensitive Skin Safe for sensitive-skin | Sensitive Skin Can irritate the skin and result in burning sensation |
Before
After 8 weeks“I liked that the product wasn’t scented. It lightened my post- summer sun spots.”
Before
After 8 weeks“My dark spots have faded significantly and my skin looks more even. My face is softer and my makeup looks so much better when wearing it.”
Before
After 8 weeks“I think this product is amazing. I’ve been using it every night before after I washed my face. I have four other family members notice that my pigmentation has lightened.”
Before
After 8 weeks“I was very doubtful that the product would work but it actually did. I have seen some significant improvement with my skin tone and brown spots on my face!”
Before
After 8 weeks“This is an amazing product that I HIGHLY recommend! I have wasted so much money on other products with each never showing any improvement, until THIS!”
Before
After 8 weeks“This product does exactly what it is supposed to do. It is a nice gel, consistency and spreads very well. It greatly improved my hyperpigmentation.”





Melanex 509
$59
Patented ODDL1007, SymWhite® 377, Niacinamide, Resveratrol, Vitamin C

Melanex 503
$59
Tretinoin, Hydroquinone, Hydrocortisone, Aloe Vera Extract, Vitamin E

Melanex 505
$59
Hydroquinone, Azelaic Acid, Allantoin, Aloe Vera Extract, Vitamin E

Melanex 507
$59
Tretinoin, Hydroquinone, Allantoin, Aloe Vera Extract, Vitamin E

SkinShield
$45
Patented Azelaic Acid Technology, Centella Asiatica, Aloe Vera, Niacinamide, Vitamin E














